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Monitoring oxygen in lungs using light amplification (Suggested Thesis Project)

Two gray circles with one red arc inside each. Illustration.

Our group works with medical laser diagnostics, specifically aimed at monitoring of oxygen in lungs using the GAs in Scattering Media Absorption Spectroscopy (GASMAS) technique. This has found successful application in the monitoring of the lung function for preterm infants, where careful monitoring of spatially distributed oxygen content can lead to optimal respiratory support and prompt detection and treatment of complications. Applications in larger children and adults have not been possible so far, due to the longer light paths involved leading to extremely low light intensities reaching the detector.

In this thesis work, you use an amplified diode laser system to investigate the detection ability in phantoms of increasing similarity to the adult lung case, starting with simpler scattering models in the lab, such as a large broiler filled with scattering material (e.g., sponge), passing via a realistic phantom lung, and (if time allows) finally to do monitoring on an excised wild boar lung. The project will be partly done in collaboration with the Neola Medical company.

Anna-Lena Sahlberg -

Monitoring lungs using light amplification -